Mente, Scot R.: search on Z-Library

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1

Potent and cellularly active 4-aminoimidazole inhibitors of cyclin-dependent kinase 5/p25 for the treatment of Alzheimer’s disease

Christopher J. Helal, Zhijun Kang, John C. Lucas, Thomas Gant, Michael K. Ahlijanian, Joel B. Schachter, Karl E.G. Richter, James M. Cook, Frank S. Menniti, Kristin Kelly, Scot Mente, Jay Pandit, Nata

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 1.18 MB

english, 2009

2

The Use of the R Language for Medicinal Chemistry Applications

Mente, Scot, Kuhn, Max

Journal:

Current Topics in Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 707 KB

english, 2012

3

A novel series of [3.2.1] azabicyclic biaryl ethers as α3β4 and α6/4β4 nicotinic receptor agonists

John A. Lowe III, Shari L. DeNinno, Jotham W. Coe, Lei Zhang, Scot Mente, Raymond S. Hurst, Robert J. Mather, Karen M. Ward, Alka Shrikhande, Hans Rollema, David E. Johnson, Weldon Horner, Roxanne Gor

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 243 KB

english, 2010

4

Dopamine D1 receptor-agonist interactions: A mutagenesis and homology modeling study

Mente, Scot, Guilmette, Edward, Salafia, Michelle, Gray, David

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 850 KB

english, 2015

5

Mapping the Binding Site of BMS-708163 on γ-Secretase with Cleavable Photoprobes

Gertsik, Natalya, am Ende, Christopher W., Geoghegan, Kieran F., Nguyen, Chuong, Mukherjee, Paramita, Mente, Scot, Seneviratne, Uthpala, Johnson, Douglas S., Li, Yue-Ming

Journal:

Cell Chemical Biology

Year:

2017

Language:

english

File:

PDF, 1.64 MB

english, 2017

6

Quantitative structure–activity relationship of phenoxyphenyl-methanamine compounds with 5HT2A, SERT, and hERG activities

Scot Mente, Randall Gallaschun, Anne Schmidt, Lorrie Lebel, Michelle Vanase-Frawley, Anton Fliri

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 265 KB

english, 2008

7

Discovery of Two Clinical Histamine H 3 Receptor Antagonists: trans - N -Ethyl-3-fluoro-3-[3-fluoro-4-(pyrrolidinylmethyl)phenyl]cyclobutanecarboxamide (PF-03654746) and trans -3-Fluoro-3-[3-fluoro-4-(pyrrolidin-1-ylmethyl)phenyl]- N -(2-methylpropyl)cyclobutanecarboxamide (PF-03654764)

Wager, Travis T., Pettersen, Betty A., Schmidt, Anne W., Spracklin, Douglas K., Mente, Scot, Butler, Todd W., Howard, Harry, Lettiere, Daniel J., Rubitski, David M., Wong, Diane F., Nedza, Frank M., N

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 3.59 MB

english, 2011

8

Measurement of Atropisomer Racemization Kinetics Using Segmented Flow Technology

Davoren, Jennifer E., Bundesmann, Mark W., Yan, Qi T., Collantes, Elizabeth M., Mente, Scot, Nason, Deane M., Gray, David L.

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 482 KB

english, 2012

9

Getting the MAX out of Computational Models: The Prediction of Unbound-Brain and Unbound-Plasma Maximum Concentrations

Mente, Scot, Doran, Angela, Wager, Travis T.

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 325 KB

english, 2012

10

Impaired β-arrestin recruitment and reduced desensitization by non-catechol agonists of the D1 dopamine receptor

Gray, David L., Allen, John A., Mente, Scot, O’Connor, Rebecca E., DeMarco, George J., Efremov, Ivan, Tierney, Patrick, Volfson, Dmitri, Davoren, Jennifer, Guilmette, Edward, Salafia, Michelle, Kozak,

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 2.99 MB

english, 2018

11

Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation

McAllister, Laura A., Butler, Christopher R., Mente, Scot, O'Neil, Steven V., Fonseca, Kari R., Piro, Justin R., Cianfrogna, Julie A., Foley, Timothy L., Gilbert, Adam M., Harris, Anthony R., Helal, C

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.32 MB

english, 2018

12

Dynamic interaction of TCNQ- with .beta.-cyclodextrin: a two-dimensional NMR exchange study

Hartzell, Cynthia J., Mente, Scot R., Eastman, Nathan L., Beckett, Jackie L.

Journal:

Journal of Physical Chemistry

Year:

1993

Language:

english

File:

PDF, 389 KB

english, 1993

13

Identification and Profiling of a Selective and Brain Penetrant Radioligand for In Vivo Target Occupancy Measurement of Casein Kinase 1 (CK1) Inhibitors

Wager, Travis T, Galatsis, Paul, Chandrasekaran, Ramalakshmi Y., Butler, Todd W, Li, Jianke, Zhang, Lei, Mente, Scot, Subramanyam, Chakrapani, Liu, Shenping, Doran, Angela C, Chang, Cheng, Fisher, Kat

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 2.52 MB

english, 2017

14

Strategies to minimize CNS toxicity: in vitro high-throughput assays and computational modeling

Wager, Travis T, Liras, Jennifer L, Mente, Scot, Trapa, Patrick

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2012

Language:

english

File:

PDF, 638 KB

english, 2012

15

Exploring Aromatic Chemical Space with NEAT: Novel and Electronically Equivalent Aromatic Template

Tu, Meihua, Rai, Brajesh K., Mathiowetz, Alan M., Didiuk, Mary, Pfefferkorn, Jeffrey A., Guzman-Perez, Angel, Benbow, John, Guimarães, Cristiano R. W., Mente, Scot, Hayward, Matthew M., Liras, Spiros

Journal:

Journal of Chemical Information and Modeling

Year:

2012

Language:

english

File:

PDF, 526 KB

english, 2012

16

Casein Kinase 1δ/ε Inhibitor PF-5006739 Attenuates Opioid Drug-Seeking Behavior

Wager, Travis T., Chandrasekaran, Ramalakshmi Y., Bradley, Jenifer, Rubitski, David, Berke, Helen, Mente, Scot, Butler, Todd, Doran, Angela, Chang, Cheng, Fisher, Katherine, Knafels, John, Liu, Shenpi

Journal:

ACS Chemical Neuroscience

Year:

2014

Language:

english

File:

PDF, 2.01 MB

english, 2014

17

Ligand–Protein Interactions of Selective Casein Kinase 1δ Inhibitors

Mente, Scot, Arnold, Eric, Butler, Todd, Chakrapani, Subramanyam, Chandrasekaran, Ramalakshmi, Cherry, Kevin, DiRico, Ken, Doran, Angela, Fisher, Katherine, Galatsis, Paul, Green, Michael, Hayward, Ma

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.75 MB

english, 2013

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